Mutation detection

Convenient mismatch endonuclease assays that are based on analysis of PCR products spanning your region of interest

Cost effective—only standard molecular biology equipment required
Save time—easy to use and compatible with high throughput processes
Detect a wide range of mutations—get the information you need

Alt-R^® Genome Editing Detection Kit »

For estimating on-target editing efficiency or assessing known off-target effects in your CRISPR experiments, we recommend using the Alt-R Genome Editing Detection Kit (also compatible with ZNF- and TALEN-driven genome editing systems). This T7 endonuclease I mismatch cleavage assay is ideal for directly analyzing your reaction products to detect multiple-base insertions and deletions.

Surveyor^® Mutation Detection Kit »

The Surveyor Mutation Detection Kit allows simple, robust detection of SNPs. The key component, Surveyor Nuclease, cleaves mismatched DNA caused by single-nucleotide polymorphisms and small insertions or deletions.