UNCOVERseq: Advancing Sensitive and Reliable Off-Target Detection in CRISPR Editing
UNCOVERseq™ is an advanced off-target detection workflow that helps researchers identify rare and unintended CRISPR editing events with greater sensitivity, precision, and reproducibility than traditional methods.
By combining enhanced laboratory methods with improved computational analysis, UNCOVERseq™ detects off-target edits at frequencies below 0.01% and identifies more validated off-target sites, providing a more complete understanding of gene-editing outcomes.
Validated across multiple editing platforms and clinically relevant cell types, UNCOVERseq supports safer therapeutic development by enabling more accurate off-target risk assessment and guide RNA selection.
